- Four Cases of Hepatocellular Carcinoma Treated with CyberKnife
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So Yeon Lee, Si Hyun Bae, Min Su Kim, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon, Joon Yeol Han, Kyu Won Chung, Young Nam Kang, Byung Ock Choi, Ihl Bohng Choi, Boo Sung Kim
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Journal of the Korean Liver Cancer Study Group. 2005;5(1):30-36. Published online June 30, 2005
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Abstract
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- CyberKnife, a new FSRT (Fractionated Stereotactic Radiotherapy) system which utilize a novel, light-weight,
and high-energy radiation source, was introduced as a newly-developed therapeutic modality for solid tumors. In
this report, we present 4 cases of hepatocellular carcinoma treated with CyberKnife. - 1. Single nodular
hepatocellular carcinoma (stage II), 2. Advanced hepatocellular carcinoma with portal vein invasion (stage IVa),
3. Advanced hepatocellular carcinoma with metastatic intraabdominal lymphadenopathy (stage IVa), 4. Advanced
hepatocellular carcinoma with right atrium invasion (stage IVb). Two patients showed complete response, and the
other two patients showed partial response without major complications. After the treatment, they are in good
general condition under observation at out-patient clinic. The present cases show that CyberKnife can give a
chance of cure for small hepatocellular carcinoma and may also be used as an additional therapeutic modality for
advanced hepatocellular carcinoma.
- A Case of Ileus Arising after Radiofrequency Ablation for the Treatment of Hepatocellular Carcinoma
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Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Young Jun Lee, Jae Young Byun
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Journal of the Korean Liver Cancer Study Group. 2005;5(1):57-59. Published online June 30, 2005
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Abstract
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- Radiofrequency ablation (RFA) was introduced as a local therapeutic approach for a variety of malignant
diseases. This modality has been reported to be one of the most feasible image-guided techniques, which can even
cure a small cancer with one session of ablation. Although this technique is generally considered safe, adverse
events attributable to the procedure have often been reported. Recently, we experienced a case of ileus arising
acutely after the completion of RFA in the treatment of a small HCC. Until now, reports on the occurrence of ileus
after RFA are almost lacking. In this rare case, we discussed the possible cause of the adverse event with a brief
review of relevant literatures.
- Small Hepatocellular Carcinoma in Dysplastic Nodule
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Chang Wook Kim, Eun Sun Jung, Jong Young Choi, Jeong Won Jang, Si Hyun Bae, Seung Kew Yoon, Chang Don Lee, Kyu Won Chung, Hee Sik Sun
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Journal of the Korean Liver Cancer Study Group. 2004;4(1):50-54. Published online June 30, 2004
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Abstract
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- Dysplastic nodule (DN) is considered as precancerous lesion of hepatocellular carcinoma (HCC). There are several evidences to support the theory about multistep progression of hepatocarcinogenesis. Recently we experienced a patient with HCC of the
odule-in-nodule pattern, namely small HCC within DN, which supported the multistep theory of hepatocarcinogenesis. The tumor was seen as a 3 cm, arterial enhancing mass with delayed wash-out patterns in the segment Ⅶ at helical CT. The patient was treated by surgical resection. A 3.0×2.5 cm mass was seen in the resected specimen. A 2.2×1.5 cm, smaller nodule was observed within this mass, i.e. the
odule-in-nodule pattern. Microscopically, various grades of HCC foci were seen within high grade DN. Because DN does not always progress to HCC, further studies are needed to evaluate what kind of DN has the high possibility of progressing of HCC at last.
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